Like its sister suburb West Columbia, Cayce lies across the Congaree River from the state capital of Columbia, and spans into both Richland and Lexington counties. Because both it and the neighboring West Columbia share road names and schools, they are sometimes referred to jointly as "Cayce-West Columbia", however they are politically separate cities.
During the Revolutionary War, the trading post in this area was seized by the British and converted into a fort. In 1817 the building was purchased by the Cayce family and used as a private residence for nearly 100 years.
The town was incorporated in 1914 and named for local businessman William J. Cayce. With its prime location, home town charm and steady growth, Cayce is convenient and appealing to business and families looking for a great place to raise their families. Cayce has that small town appeal without the hectic pace and pressures of the big city, but is convenient to all of amenities afforded by the city of Columbia.
Within Cayce’s municipal boundaries are the Columbia Metropolitan Airport, Interstate 26 and Interstate 77.
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